Difference Of Low, Medium, And High Molecular Weight Hyaluronic Acid In Injection Use

  • Molecular Weight:

 

   Low molecular weight hyaluronic acid: Typically ranges between 400,000 to 1,000,000 Daltons (Da). Due to its smaller molecular size, it is more easily absorbed by the body, resulting in faster metabolism.

  

   Medium molecular weight hyaluronic acid: It falls between low and high molecular weight, with specific ranges varying by product. Its texture is soft, suitable for soft tissue filling and wrinkle reduction.

  

   High molecular weight hyaluronic acid: Generally ranges between 1,800,000 to 2,200,000 Da. It has a firmer texture, providing longer-lasting filling effects, making it suitable for shaping procedures.

  •  Filling Effect

 

   Low molecular weight hyaluronic acid: Primarily used for superficial filling of the epidermal and dermal layers, penetrating the dermis to increase skin elasticity, delay skin aging, and effectively reduce wrinkles.

  

   Medium molecular weight hyaluronic acid: Suitable for soft tissue filling and improvement of deep wrinkles, such as nasolabial folds, lips, and areas with pronounced wrinkles.

  

   High molecular weight hyaluronic acid: Mainly used for deep tissue filling and shaping procedures such as nose augmentation, chin augmentation, buttock augmentation, and breast augmentation, creating distinct contours.

  •  Injection Method

 

   Low molecular weight hyaluronic acid: Often administered via point-by-point injections for fine adjustments, improving skin texture and moisturizing effects.

  

   Medium molecular weight hyaluronic acid: Typically injected into the mid to deep layers of the dermis, primarily for filling depressions and wrinkles.

  

   High molecular weight hyaluronic acid: Commonly used in shaping procedures like nose augmentation, requiring specific injection paths to ensure filling and shaping effects are achieved.

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